Sglt2 inhibitor activates the sting/irf3/ifn-β pathway and induces immune infiltration in osteosarcoma

HIGHLIGHTS

• who: Wei Wu from the Syngeneic tumor model treatment protocol All animal procedures were performed in a specific pathogen free situation according to the guidelines of the ethics committee of Tongji Medical College, Huazhong University of Science and Technology (Wuhan, China)C BL/, mice (6, weeks, male) were purchased from Vitalriver (Beijing, China). The animal experimental procedures were approved by the Ethics Committee of Tongji Medical College (HUST, Wuhan, China). K , cells (, u00d7 , in , u03bcl , u00d7 PBS) were injected s.c. into the right flank of the mice and the mice were randomly divided into four groups . . .
  

   

  

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