A novel aryl hydrocarbon receptor antagonist hbu651 ameliorates peripheral and hypothalamic inflammation in high-fat diet-induced obese mice

HIGHLIGHTS

  • who: Sora Kang and colleagues from the Department of Neuroscience, Graduate School, Kyung Hee University, Seoul, Republic of Korea have published the research work: A Novel Aryl Hydrocarbon Receptor Antagonist HBU651 Ameliorates Peripheral and Hypothalamic Inflammation in High-Fat Diet-Induced Obese Mice, in the Journal: (JOURNAL) of 10/Nov/2022
  • what: The authors evaluated the anti-obesity and anti-inflammatory activity of a novel AhR
  • how: To evaluate therapeutic efficacy on insulin resistance the authors investigated the effect of HBU651 on inflammation using LPS-stimulated BV2 cells and an HFD-induced obese . . .

     

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