Dna methylation-based classification of sinonasal tumors

HIGHLIGHTS

  • who: Philipp Jurmeister from the (UNIVERSITY) have published the article: DNA methylation-based classification of sinonasal tumors, in the Journal: (JOURNAL) of 31/03/2022
  • what: By further integrating mutational profiling and mass spectrometry-based proteomics, the authors provide sound evidence that tumors with SNUC morphology consist of four distinct epigenetic subclasses which are supported by different driver mutations landscape and protein expression profiles. The authors provide a machine_learning-based algorithm for reliable classification of diagnostic samples which may improve the histopathological diagnosis of challenging cases. D Receiver operating characteristic (ROC) curve of the support . . .

     

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