Involvement of the sting signaling in covid-19

HIGHLIGHTS

  • who: Ruoxuan Xiao and Ao Zhang from the Shandong University, China have published the paper: Involvement of the STING signaling in COVID-19, in the Journal: (JOURNAL)
  • how: The results showed that both S protein and SARS-CoV-2 induced syncytium formation in HeLa-ACE2 cells and then led to production of micronuclei. Transcriptome data showed that at the time of diagnosis the content of STING protein was increased in the blood of patients with mild or moderate symptoms whereas there is no significant change in the severe patients .
  • future: More detailed mechanistic . . .

     

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