HIGHLIGHTS
- who: Xin Chen et al. from the Department China Medical University have published the research work: Authorship note: XC, TL, and JW contributed equally to this work. Conflict of interest: The authors have declared that no conflict of interest exists, in the Journal: (JOURNAL)
- what: The study explored the important molecular events and developed a subtype classification system with distinct targeted therapy strategies for different subtypes of TP53mut tumors. This study provided guidance in determining the treatment of patients with TP53mut with COCA3 subtype.
- how: For ICB treatment cohort the authors selected the . . .
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