Cyp17a2 is involved in testicular development and fertility in male nile tilapia, oreochromis niloticus

HIGHLIGHTS

  • who: Lanying Yang from the Yat-sen University, China have published the research work: Cyp17a2 is involved in testicular development and fertility in male Nile tilapia, Oreochromis niloticus, in the Journal: (JOURNAL)

SUMMARY

    In the present study, a null mutation line of cyp17a2 gene was constructed by CRISPR/Cas9 technology to assess the functional implication of Cyp17a2 in teleostean steroidogenesis and gonadal maintenance. Knockout of the cyp17a2 gene by CRISPR/Cas9 A homozygous mutation line of cyp17a2 was constructed in tilapia to elucidate the functions of Cyp17a2 in fish steroidogenesis, spermatogenesis, and male . . .

     

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