A new glutathione-cleavable theranostic for photodynamic therapy based on bacteriochlorin e and styrylnaphthalimide derivatives

HIGHLIGHTS

  • who: Marina A. Pavlova and colleagues from the , Moscow, Russia Faculty of Petroleum Chemistry and Polymeric Materials, DMendeleev University of Chemical Technology have published the research work: A New Glutathione-Cleavable Theranostic for Photodynamic Therapy Based on Bacteriochlorin e and Styrylnaphthalimide Derivatives, in the Journal: Biosensors 2022, 12, 1149. of /2022/
  • what: The authors report conjugate BChl-S-S-NI the second-generation photosensitizer e6 (BChl) and fluorophore (NI) which is cleaved into individual functional fragments in the intracellular medium. The authors propose to use a fundamentally different strategy which consists of using two functional . . .

     

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