The spindle assembly checkpoint and the spatial activation of polo kinase determine the duration of cell division and prevent tumor formation

HIGHLIGHTS

• who: Emmanuel Gallaud and collaborators from the Montru00e9al, Quebec, CanadaEditor: Yan Song, Peking University, CHINA have published the Article: The spindle assembly checkpoint and the spatial activation of Polo kinase determine the duration of cell division and prevent tumor formation, in the Journal: (JOURNAL) of March/14,/2022
• what: Using asymmetrically dividing Drosophila neural stem cells (NSCs) the authors show that Polo kinase activity levels determine timely Cyclin B degradation and mitotic progression independent of the spindle assembly checkpoint (SAC). The authors show that Aurora Adependent activation of Polo is the major event that promotes . . .
  

   

  

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