HIGHLIGHTS
- who: Leiv- Otto Watne from the ) Oslo Delirium Research Group, Oslo University, Oslo, London, UK have published the paper: Cerebrospinal fluid quinolinic acid is strongly associated with delirium and mortality in hip fracture patients, in the Journal: (JOURNAL)
- what: The authors propose that systemic inflammation, triggered by e_g tissue damage or infection activates IDO, resulting in disrupted balance of the kynurenines and, ultimately, delirium. While malfunction of the KP is linked to both neurodegenerative diseases (such as Alzheimer`s disease and Huntington`s disease ) and mental disorders (depression, psychosis, and schizophrenia) , here the authors provide . . .
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