Dietary iron overload enhances western diet induced hepatic inflammation and alters lipid metabolism in rats sharing similarity with human dios

HIGHLIGHTS

  • who: Sakura Fujiwara from the LaboratoryMetropolitan University have published the research work: Dietary iron overload enhances Western diet induced hepatic inflammation and alters lipid metabolism in rats sharing similarity with human DIOS, in the Journal: Scientific Reports Scientific Reports
  • what: Next, the authors focused on the upstream pathway of NFu03baB. In this study, dietary iron overload exacerbates Western diet-induced hepatic inflammation with upregulation of cytokines such as TNFu03b1 and IFNu03b3; similar findings were obtained in the previous studies with rodent NAFLD u00admodels22,55.
  • how: The authors evaluated hepatic iron content in the . . .

     

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