Correlations between 4β-hydroxycholesterol and hepatic and intestinal cyp3a4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range

HIGHLIGHTS

• who: Kine Eide Kvitne from the (UNIVERSITY) have published the research work: Correlations between 4u03b2-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range, in the Journal: (JOURNAL)
• what: This study investigated the 4u03b2OHC concentrations and hepatic and intestinal CYP3A4 protein expression and ex vivo microsomal activity in paired liver and jejunum samples as well as in vivo CYP3A4 phenotyping (midazolam) in patients with a wide body weight range. The authors also report a negative correlation between BMI and 4u03b2OHC . . .
  

   

  

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