Transgenerationally transmitted dna demethylation of a spontaneous epialleles using crispr/dcas9-tet1cd targeted epigenetic editing in arabidopsis

HIGHLIGHTS

  • who: Min Wang et al. from the State Key Laboratory of Tree Genetics and Breeding, Forestry University, Harbin, China have published the paper: Transgenerationally Transmitted DNA Demethylation of a Spontaneous Epialleles Using CRISPR/dCas9-TET1cd Targeted Epigenetic Editing in Arabidopsis, in the Journal: (JOURNAL) of 10/04/2021
  • what: The authors show that the CRISPR/dCas9-TET1cd system can be used to target the of hypermethylated NMR19-4 region to reduce the level of thereby increasing the expression of PPH and accelerating leaf senescence. In the experiments , the authors attempted to demethylate NMR19-4 via . . .

     

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