Targeting the heterogeneous genomic landscape in triple-negative breast cancer through inhibitors of the transcriptional machinery

HIGHLIGHTS

• who: Vera E. van der Noord and collaborators from the Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, CC Leiden, The Netherlands have published the article: Targeting the Heterogeneous Genomic Landscape in Triple-Negative Breast Cancer through Inhibitors of the Transcriptional Machinery, in the Journal: Cancers 2022, 4353 of 27/05/2022
• what: In this review the authors discuss how inhibitors of the transcriptional machinery can effectively target genetic abnormalities in TNBC and how these abnormalities can influence sensitivity to these inhibitors. As will be discussed in this review . . .
  

   

  

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