Optimization of transcription factor genetic circuits

HIGHLIGHTS

  • who: Steven A. Frank from the Department of Ecology and Evolutionary Biology, University of California, Irvine, CA, USA have published the article: Optimization of Transcription Factor Genetic Circuits, in the Journal: Biology 2022, 11, 1294. of 31/08/2022
  • what: In Figure 1a, the authors seek a parameter combination that minimizes the loss measured as the distance between the target circadian pattern shown in the gold curve and the transformed abundance of TF 1 in the green curve.
  • how: This article introduces a computational method to optimize TF networks. This article introduces several . . .

     

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