HIGHLIGHTS
- who: Jin-Hua Bo and collaborators from the Cardiovascular Disease Translational Medicine, Department of Physiology, Nanjing Medical University, Nanjing, China have published the paper: Dexmedetomidine Attenuates Lipopolysaccharide-Induced Sympathetic Activation and Sepsis via Suppressing Superoxide Signaling in Paraventricular Nucleus, in the Journal: Antioxidants 2022, 2395 of /2022/
- what: The authors aimed to determine the central roles and mechanisms of DEX in attenuating sympathetic activity and inflammation in sepsis. This study has shown that NADPH oxidase-derived superoxide production in the PVN mediates the inhibitory effects of DEX on sympathetic activity as the authors described above . . .
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