The role of mitochondrial fission proteins in mitochondrial dynamics in kidney disease

HIGHLIGHTS

  • who: Lingyu Qin and Shuhua Xi from the Department of Environmental Health, School of Public Health, China Medical University, No, Puhe Road have published the article: The role of Mitochondrial Fission Proteins in Mitochondrial Dynamics in Kidney Disease, in the Journal: (JOURNAL)

SUMMARY

    In contrast, the mitochondrial fusion_proteins MFN1/MFN2 also play an important role in cell proliferation. Promoting mitochondrialfission-related protein expression increases mitochondrial network fragmentation, while increasing mitochondrial fission promotes cytochrome C release from mitochondria and thus increases apoptosis, while inhibiting mitochondrial-fission-related proteins reduces mitochondrial fission and inhibits apoptosis . . .

     

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