HIGHLIGHTS
- who: Paolo Bernardi and Evgeny Pavlov from the (UNIVERSITY) have published the research work: Mitochondrial Permeability Transition, in the Journal: Cells 2022, 11, 3866. of 23/Nov/2022
SUMMARY
The mitochondrial permeability transition (PT) is a phenomenon that can be broadly defined as an increase in the permeability of the mitochondrial inner membrane. The PT disrupts the process of mitochondrial oxidative_phosphorylation, dramatically affecting mitochondrial function with profound consequences on cellular and organism function. In most cases, the PT is linked to the opening of a large conductance pore: the mitochondrial permeability transition pore . . .
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