A mouse model with widespread expression of the c9orf72-linked glycine-arginine dipeptide displays non-lethal als/ftd-like phenotypes

HIGHLIGHTS

• who: Brandie Morris Verdone from the Jack Farber Institute Jefferson University have published the Article: A mouse model with widespread expression of the C9orf72-linked glycine-arginine dipeptide displays non-lethal ALS/FTD-like phenotypes, in the Journal: Scientific Reports Scientific Reports
• what: This observation could suggest a developmental delay as opposed to a pure distal axonal deficit, or motor neuron compensation since the authors report a reduction in ChAT-positive neurons in 6-month-old female mice. Because the authors aimed to understand if an overall difference in the gait of GR50-GFP and . . .
  

   

  

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