HIGHLIGHTS
- who: Chisato Kinoshita and colleagues from the Department of Pharmacology, Teikyo University School of Medicine, Kaga, Itabashi, Tokyo, Japan have published the article: Glutathione Depletion and MicroRNA Dysregulation in Multiple System Atrophy: A Review, in the Journal: (JOURNAL)
- what: In this review the authors focused on the relation between deficiency miRNA dysregulation and oxidative stress and their close relation with MSA pathology. Most of the studies assessing the pathogenesis of MSA have focused on the mechanisms underlying intracellular accumulation of u03b1-syn, an approximately 14.5-kDa protein composed of 140 amino_acids that is physiologically . . .
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