Blockade of cholecystokinin type 2 receptors prevents the onset of vincristine-induced neuropathy in mice

HIGHLIGHTS

  • who: Amandine Bernard and colleagues from the University of Limoges, Limoges, France have published the research: Blockade of Cholecystokinin Type 2 Receptors Prevents the Onset of Vincristine-Induced Neuropathy in Mice, in the Journal: Pharmaceutics 2022, 14, 2823. of /2022/
  • what: The authors thus sought to elucidate the contribution of CCK2R to VCR-induced pain and to examine if the inhibition of CCK2R may be a potentially effective strategy to prevent the development of VCR-induced neuropathic pain. The authors aimed to investigate the potential changes in pathways following VCR exposure. The neuroprotective effects obtained . . .

     

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