HIGHLIGHTS
- who: Victor Naumenko from the Research Institute University of have published the research: Repeated dosing improves oncolytic rhabdovirus therapy in mice via interactions with intravascular monocytes, in the Journal: (JOURNAL) of 12/08/2021
- what: In this study tumor infection and antitumor responses were observed to be higher upon systemic administration of two VSVu0394M51 doses as compared to a single dose treatment regime in CT-26LacZ and M3-9-M tumor models. This study shows that the antitumor activity of OV delivered as repeat doses fundamentally differs from the welldescribed mechanisms of single-dose OV . . .
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