Multimodal chromatin profiling using nanobody-based single-cell cut&tag

HIGHLIGHTS

• who: Marek Bartosovic from the (UNIVERSITY) have published the research: Multimodal chromatin profiling using nanobody-based single-cell CUT&Tag, in the Journal: (JOURNAL) of 28/09/2022
• what: The authors focused on the oligodendrocyte lineage, and the authors used the combined WNN embedding to generate pseudo-time Nature Biotechnology of oligodendrocyte differentiation (Fig 6a). The authors show that nano-CT could provide direct measurement of time-resolved dynamics of chromatin enhancer activation, resolve distinct waves of repressive H3K27me3 and define chromatin velocity in single cells.

SUMMARY

The authors describe nano . . .

 



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