Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies

HIGHLIGHTS

• who: Kevin A. Murray from the DepartmentsUniversity of have published the Article: Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies, in the Journal: (JOURNAL) of 24/05/2021
• what: The authors show that the amyloid aggregation of KRT8 can be seeded by ASH liver tissue extracts implicating amyloid interactions in alcoholic liver disease. In this step the authors assess whether a mutation increases the propensity of the sequence to form a pleated sheet as opposed to a kinked one. In this analysis the authors compared the relative frequencies at . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.