The mitochondrial chaperone trap1 regulates f-atp synthase channel formation

HIGHLIGHTS

• who: Giuseppe Cannino from the (UNIVERSITY) have published the research work: The mitochondrial chaperone TRAP1 regulates F-ATP synthase channel formation, in the Journal: (JOURNAL) of 25/05/2022
• what: The authors demonstrate that TRAP1 enhances the enzymatic activity of F-ATP synthase and abrogates the inhibitory effect of CyPD. The authors demonstrate that at least two proteins, CyPD and TRAP1, regulate PTP opening in electrophysiology experiments where a purified F-ATP synthase was reconstituted into lipid bilayers.
• how: The authors carried out these tripartite split-GFP experiments on malignant peripheral nerve sheath . . .
  

   

  

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