Cerebellar Synaptic Defects and Abnormal Motor Behavior in Mice Lacking � – and -Dystrobrevin

HIGHLIGHTS

• who: ERG and collaborators from the Departments of Pediatrics, Anatomy and Neurobiology, Psychiatry, and Otolaryngology, Washington University School of Medicine, StLouis, Missouri have published the article: Cerebellar Synaptic Defects and Abnormal Motor Behavior in Mice Lacking � - and -Dystrobrevin, in the Journal: (JOURNAL) of March/15,/2006
• what: The authors show here that dystrophin is lost from a subset of inhibitory synapses in DKO brain and that DKOs exhibit synaptic and behavioral defects similar, although not identical, to those seen in dystrophin-deficient (mdx) mice. The confidence in the distribution the authors report stems from the . . .
  

   

  

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