Mitochondria directly sense osmotic stress to trigger rapid metabolic remodeling via regulation of pyruvate dehydrogenase (pdh) phosphorylation

HIGHLIGHTS

  • who: Takeshi Ikizawa from the Laboratory of Cell Signaling, Graduate School of Pharmaceutical, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo, Japan have published the Article: Mitochondria directly sense osmotic stress to trigger rapid metabolic remodeling via regulation of pyruvate dehydrogenase (PDH) phosphorylation, in the Journal: (JOURNAL)
  • what: The authors demonstrate that Warburg-like remodeling is required for HeLa cells maintain ATP levels and survive under hyperosmotic conditions. The authors demonstrate that glucose metabolic remodeling from oxidative_phosphorylation (OXPHOS) to aerobic glycolysis (a Warburg-like effect) is rapidly triggered upon hyperosmotic stress both in HeLa cells . . .

     

    Logo ScioWire Beta black

    If you want to have access to all the content you need to log in!

    Thanks :)

    If you don't have an account, you can create one here.

     

Scroll to Top

Add A Knowledge Base Question !

+ = Verify Human or Spambot ?