Paclitaxel inhibits kcnq channels in primary sensory neurons to initiate the development of painful peripheral neuropathy

HIGHLIGHTS

• who: Zizhen Wu et al. from the Department of Neurobiology, University of Texas Medical Branch, Galveston, TX, USA have published the paper: Paclitaxel Inhibits KCNQ Channels in Primary Sensory Neurons to Initiate the Development of Painful Peripheral Neuropathy, in the Journal: Cells 2022, 11, x FOR PEER REVIEW of /2022/
• what: The authors aimed to uncover a novel mechanism underlying the pathogenesis of PIPN. The authors aim to investigate the molecular mechanisms underlying paclitaxelinduced acute excitation of DRG neurons and its contribution to the development of PIPN. By combining a transgenic approach and electrophysiological recordings . . .
  

   

  

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