HIGHLIGHTS
- who: Malvika Sardana and colleagues from the Universitu00e9 Paris-Saclay, Inserm, CNRS, CEA, Laboratoire d`Imagerie Biomu00e9dicale Multimodale Paris-Saclay (BioMaps), Orsay, France have published the article: Isotopic Radiolabeling of Crizotinib with Fluorine-18 for In Vivo Pet Imaging, in the Journal: Pharmaceuticals 2022, 1568 of 17/Nov/2022
- what: Aiming at developing a new tool to explore the brain penetration of crizotinib with PET imaging and investigating means to enhance the brain exposure, the authors report herein the synthesis of an original iodonium ylide precursor to achieve the challenging isotopic radiolabeling of crizotinib with . . .
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