Loss of surface transport is a main cellular pathomechanism of crb2 variants causing podocytopathies

HIGHLIGHTS

  • who: Annika Mou0308ller-Kerutt and colleagues from the University Hospital of Muenster (UKM), Internal Medicine (MedD), Muenster, Germany Muenster, Muenster, Germany have published the research work: Loss of surface transport is a main cellular pathomechanism of CRB2 variants causing podocytopathies, in the Journal: (JOURNAL)
  • what: The authors report the development of a robust in_vitro assay, suitable to confirm or validate given CRB2 disease-associated variants and as a screening tool to investigate the pathogenic potential of novel, so far uncharacterized CRB2 variants.
  • how: For evaluation of the live-cell imaging data the authors . . .

     

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