Tie-line analysis reveals interactions driving heteromolecular condensate formation

HIGHLIGHTS

  • who: Daoyuan Qian and colleagues from the CentreUniversity of Lensfield Road, Cambridge, EW, United Kingdom have published the article: Tie-Line Analysis Reveals Interactions Driving Heteromolecular Condensate Formation, in the Journal: (JOURNAL) of 30/Dec/2022
  • what: The authors develop an approach to determine tie-line gradients in ternary biomolecular phase-separation systems based on measurements of the dilute phase concentration of only one component. The authors show that the sign of the tie-line gradient is related to the cross-interaction energy between the polymers in the system and discriminates between associative and segregative . . .

     

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