Endogenous retroviral sequences behave as putative enhancers controlling gene expression through hp1-regulated long-range chromatin interactions

HIGHLIGHTS

  • who: Su00e9bastien Calvet and collaborators from the Institut de Recherche en Cancu00e9rologie de Montpellier (IRCM), University of Montpellier, Inserm, Paris, France have published the research: Endogenous Retroviral Sequences Behave as Putative Enhancers Controlling Gene Expression through HP1-Regulated Long-Range Chromatin Interactions, in the Journal: Cells 2022, 11, x FOR PEER REVIEW that Mbd1 of 16/03/2022
  • what: By studying two ERVs located upstream of genes upregulated upon loss of HP1 Mbd1 and Trim24 the authors show that these HP1-dependent ERVs either alternative promoters or enhancers forming a loop with promoters of genes . . .

     

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