HIGHLIGHTS
- who: Raphaela Gonu00e7alves Barros Perri and colleagues from the Department of Biotechnology, University of Ribeiru00e3o Preto, Ribeiru00e3o Preto, SP, Brazil have published the research: Silencing of the GluN1-NMDA Glutamate Receptor Subunit by Intranasal siRNA Increases the Latency Time for Seizures in the Pilocarpine Rodent Model of Epilepsy, in the Journal: Pharmaceuticals 2022, 1470 of /2022/
- what: This work evaluated the potential silencing effect of intranasal administration of an siRNA conjugate against the GluN1 subunit in animals submitted to the pilocarpine model of epilepsy. Given the NMDA receptor function gain in TLE, this work aims . . .
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