Mechanisms of egfr-tki-induced apoptosis and strategies targeting apoptosis in egfr-mutated non-small cell lung cancer

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  • who: Shigetoshi Nishihara and colleagues from the Division of Gastroenterology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan have published the Article: Mechanisms of EGFR-TKI-Induced Apoptosis and Strategies Targeting Apoptosis in EGFR-Mutated Non-Small Cell Lung Cancer, in the Journal: Genes 2022, 2183 of 20/Nov/2022
  • what: This trial showed that patients with high BIM mRNA expression had longer PFS upon erlotinib treatment (12.9 months; 95% CI: 9.7-23.9) than patients with low/intermediate BIM mRNA expression did (7.2 months; 95% CI: 2.6-12 . . .

     

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