Dna nanoflowers’ amelioration of lupus symptoms in mice via blockade of tlr7/9’s signal

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  • who: Jing Wang and Mingzhe Gan from the Laboratory Animal Center of Soochow University, Suzhou, China have published the Article: DNA Nanoflowersu2019 Amelioration of Lupus Symptoms in Mice via Blockade of TLR7/9u2019s Signal, in the Journal: (JOURNAL)
  • what: In this paper, when TLR7 or TLR9 was blocked alone, the IRS-661-nanoflower-treated group and the IRS-869-nanoflower-treated group showed better amelioration of lupus symptoms. The IRS-661-nanoflower-treated group in the study showed a very significant immunosuppressive effect, decreasing autoantibodies and alleviating lupus nephritis in the lupus model. The study . . .

     

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