HIGHLIGHTS
- who: Jingru Wang et al. from the School of Life Sciences, Guangzhou University, Guangzhou, China have published the paper: Cross-Linking and Functional Analyses for Dimerization of a Cysteine Mutant of Glycine Transporter 1, in the Journal: (JOURNAL)
- what: This study provides new insights into structural and elements regulating GlyT1 transport activity through its dimerization or oligomerization.
- how: The authors examined the influence of an intramolecular ion pair on L288C dimerization and transport activity. Consistent with previous reports on hDAT the results showed that CuP cross-linking of GlyT1 L288C only produced dimerization . . .
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