A novel protocol for the synthesis of 1,2,4-oxadiazoles active against trypanosomatids and drug-resistant leukemia cell lines

HIGHLIGHTS

• who: Paulo Pitasse-Santos and collaborators from the Instituto Quu00edmica, Universidade Federal Rural Rio Janeiro, Seropu00e9dica, Rio Janeiro, Brazil have published the research work: A Novel Protocol for the Synthesis of 1,2,4-Oxadiazoles Active against Trypanosomatids and Drug-Resistant Leukemia Cell Lines, in the Journal: (JOURNAL) of 12/03/2022
• what: The novel method employed for the synthesis of the 1,2,4-oxadiazole ring was efficient for the preparation of compounds 9-25.
• how: A summary of the pharmacokinetic and toxicity analysis results is presented in Table 7.

 

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