Regulated ire1α-dependent decay (ridd)-mediated reprograming of lipid metabolism in cancer

HIGHLIGHTS

• who: Aitor Almanza from the National University have published the Article: Regulated IRE1u03b1-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors employed unbiased lipidomic and transcriptomic approaches to investigate the contribution of IRE1u03b1 signaling to lipid metabolism in TNBC. Among the potential IRE1u03b1 targets involved in TAG metabolism, the authors focused the attention on DGAT2, as this gene encodes an ER membrane-localized enzyme that catalyzes the terminal, rate-limiting_step in TAG synthesis26. The authors demonstrate RIDD activity in reprogramming of lipid metabolism . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.