The extrafollicular response is sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus

HIGHLIGHTS

  • who: Lasse F. Voss and collaborators from the The University of Texas Health Science Center at San Antonio, United States have published the research: The extrafollicular response is sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus, in the Journal: (JOURNAL)
  • what: The aim of this study was to investigate the contribution of the extrafollicular pathway to autoimmune disease development. The authors propose that therapeutic targeting of low quality and poorly controlled extrafollicular responses could be a desirable strategy to curb autoreactivity, as it would leave intact the more stringently controlled and . . .

     

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