Transcriptional regulation of satb1 in mouse trophoblast stem cells

HIGHLIGHTS

  • who: December et al. from the Ludwig Maximilian University of Munich, Germany have published the research work: Transcriptional regulation of Satb1 in mouse trophoblast stem cells, in the Journal: (JOURNAL)
  • what: Taken together, the authors propose a model of ELF5-SATB1 interaction that regulates Satb1 expression in the trophoblast stem-state .
  • how: The authors detected Satb1 transcript variants that are preferentially expressed in trophoblast cells and identified their promoters.

SUMMARY

    SATB proteins bind to AT-rich elements in matrix-attachment regions of actively transcribing DNA and interact with chromatin . . .

     

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