Cancer and radiosensitivity syndromes: is impaired nuclear atm kinase activity the primum movens?

HIGHLIGHTS

  • who: Laura El Nachef et al. from the Inserm, Unit, Radiation: Defense, Health and Environment, Centre Lu00e9on-Bu00e9rard, Lyon, France have published the research: Cancer and Radiosensitivity Syndromes: Is Impaired Nuclear ATM Kinase Activity the Primum Movens?, in the Journal: Cancers 2022, 14, 6141. of /2022/
  • what: The model may be completed with mechanisms describing the fate of the DNA damage when induced during the G2/M phase.
  • how: While these two requirements involve two different functions that should be both impaired the review shows that the major cancer and radiosensitivity syndromes are . . .

     

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