Integracides: tetracyclic triterpenoids from fusarium sp.—their 5-lipoxygenase inhibitory potential and structure-activity relation using in vitro and molecular docking studies

HIGHLIGHTS

  • who: Maan T. Khayat et al. from the Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia have published the article: Integracides: Tetracyclic Triterpenoids from Fusarium sp.u2014Their 5-Lipoxygenase Inhibitory Potential and Structure-Activity Relation Using In Vitro and Molecular Docking Studies, in the Journal: Life 2022, 12, x FOR PEER REVIEW of 16/Nov/2022
  • what: A new tetracyclic triterpenoid, integracide L (1) and two metabolites (2 and 3), were purified from Fusarium sp.
  • future: In_vivo and mechanistic investigations are needed.

SUMMARY

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