HIGHLIGHTS
- who: Malgorzata Kloc and Jacek Z. Kubiak from the Houston, TX, USA The University have published the article: Monocyte and Macrophage Function Diversity, in the Journal: (JOURNAL) of 10/Oct/2022
SUMMARY
In their most primeval function, macrophages phagocytose and kill microbes, such as Gram-negative bacteria, which contain lipopolysaccharides (LPS) in their cell wall. Thim-Uam et_al describe how splenectomy- or LPS- induced gut barrier defect, which causes severe bacteremia followed by endotoxemia-induced LPS tolerance, affects macrophage functions. Macrophages are known to be major players in inflammatory diseases such as hypertension . . .
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