Transcriptome-wide association study reveals cholesterol metabolism gene lpl is a key regulator of cognitive dysfunction

HIGHLIGHTS

  • who: Wei Hu from the Nanjing Medical University, China have published the research: Transcriptome-wide association study reveals cholesterol metabolism gene Lpl is a key regulator of cognitive dysfunction, in the Journal: Microbiome
  • what: The BXD hippocampus transcriptomic data set used in this study provides estimates of mRNA expression in the adult hippocampus of 67 BXD recombinant inbred strains, two parental strains (C57BL/6J and DBA2/J), and two reciprocal F1 hybrids. The authors demonstrate, among the 280 genes related to lipid metabolism, that the Lpl plays a pivotal role in regulating cognitive function, as . . .

     

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