On the choice of negative examples for prediction of host-pathogen protein interactions

HIGHLIGHTS

• who: December and colleagues from the Purdue University, United States have published the research work: On the choice of negative examples for prediction of host-pathogen protein interactions, in the Journal: (JOURNAL)
• what: Most of the work in this area focuses on prediction of interactions from sequence, especially using deep learning techniques. The authors focus on one issue related to the choice of negative examples that keeps showing up in various guises.
• how: To demonstrate the effect of using similarity-based sampling on HPI prediction accuracy the authors implemented the strategy proposed by . . .
  

   

  

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