HIGHLIGHTS
- who: Maha Abdeladhim from the National Institutes of Health (NIH), United States University of East London have published the research: In or out of control: Modulating regulatory T cell homeostasis and function with immune checkpoint pathways, in the Journal: (JOURNAL)
- what: The study showed that while Treg numbers were diminished in the periphery, the ex vivo functionality of Tregs were improved upon Abatacept treatment .
- how: This result was consistent with loss of suppressive function in CD28-deficient Tregs and failed to maintain immune surveillance in_vivo . Similar observation was made in the context of . . .
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