HIGHLIGHTS
SUMMARY
As is associated with a variety of immune cells, including CD4+, CD8+ T_cells, and macrophages, which produce cytokines, particularly TNF-α and TGF-β, which are important in the inflammatory process by causing inflammation, fibrosis, and ossification at enthesitis. The authors utilized the terms "Ankylosing Spondylitis" and "Inflammatory Bowel Disease" to search the GEO (https://www.ncbi.nlm.nih.gov/geo/) database for AS and IBD gene_expression profiles. The following were the criteria for inclusion: array-based expression profiling or high-throughput mRNA sequencing; case and control groups are required for gene_expression profiling; to guarantee that . . .
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