Pharmacokinetics effects of chuanxiong rhizoma on warfarin in pseudo germ-free rats

HIGHLIGHTS

  • who: UPLC-/ et al. from the Taiwan China Pharmaceutical University, China have published the Article: Pharmacokinetics effects of chuanxiong rhizoma on warfarin in pseudo germ-free rats, in the Journal: (JOURNAL) of 22/02/2019
  • what: This study showed that the ciprofloxacin-induced germfree condition and co-administration of Chuanxiong Rhizoma aqueous extracts decreased the relative abundance of Dubosiella. The study provided more theoretical reasons for the combination of Chuanxiong Rhizoma and warfarin from the visual of gut microbiota.
  • how: The HPLC analytical results are shown in Supplementary Figure S1. These results indicated . . .

     

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