HIGHLIGHTS
- who: Monique M.A. de Almeida from the Faculty University of Alberta, Edmonton, AB T G , Canada have published the paper: Fractalkine enhances oligodendrocyte regeneration and remyelination in a demyelination mouse model, in the Journal: (JOURNAL) of February/14,/2023
- what: Using a cuprizone mouse model of demyelination the authors show that infusion of fractalkine (CX3CL1) into the demyelinated murine brain increases novo oligodendrocyte formation and enhances remyelination in the corpus callosum and cortical gray matter. The authors show that activated OPCs and microglia/macrophages express fractalkine receptor CX3CR1 in vivo and that in OPC . . .
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