Combined obstructive airflow limitation associated with interstitial lung diseases (o-ild): the bad phenotype ?

HIGHLIGHTS

  • who: Julien Guiot from the hyperinflation can lead to an overestimation of the total lung capacity (TLC) than can underestimate ILD severityIn most clinical trials evaluating anti-fibrotic therapies, ILD patients exhibiting significant airway obstruction are systematically excluded, reducing the validation of antifibrotic treatments for this subset of patients. Therefore, there is an unmet clinical need to better define the subset of, ILD patients and subsequently investigate the use of ILD-targeted therapies (such as antifibrotics) in this group. The aim of this descriptive and explorative study was to describe the phenotype and functional characteristics of, ILD . . .

     

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