HIGHLIGHTS
- who: Marie-Therese Holzer from the University Hospital Wuerzburg, Josefu2011Schneideru2011Str2, Wuerzburg, Germany have published the paper: Mitigated suppressive function of regulatory T cells (Treg) upon Th17-inducing cytokines in oligo- and polyarticular Juvenile Idiopathic Arthritis (JIA) patients, in the Journal: (JOURNAL)
- what: The experiments show an increased FoxP3-expression in Treg by Th17-inducing cytokines with concomitant mitigated suppressive function.
SUMMARY
T_cells play a central role in the pathogenesis of Juvenile Idiopathic Arthritis (JIA) with activated T_cells accumulating in inflamed joints. Research has been focusing on the balance of Th17 cells . . .
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